I came across this a long time ago and believe it to be true to this day. I'm not a doctor and this isn't medical advice.
I don't think they block the benefits and have definitely helped my husband NoFap. He has been on an SSRI a while now and after a couple of months his urges to M reduced a lot and now he really doesn't get any at all. PIV is still fine, he lasts a long time now which is better for us.